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The building of organs during embryogenesis constitutes one of the most fascinating, but also least understood developmental processes. Coordinated gene action directs the developmental fate of cells to assemble into complex, three-dimensional structures with characteristic shape, size, and physiological properties. The acquisition of different cell fates initiates an elaborate interplay of cell proliferation, migration, growth, differentiation and death, bringing together cellular ensembles in a precise temporal and spatial manner. For many scientists, great research starts with a question. For members of my lab, the mechanisms which intrinsic and extrinsic factors use to generate cell diversity, coordinate morphogenetic cell movements, and regulate assembly of the different tissue types comprising an organ, define one of the central questions in science today and shapes the foundation of our research objectives. |
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full time, summer 2009 (8-10 weeks) Opportunity to extend into fall 2009-spring 2010 |
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BIO41 (genetics or equivalent); Enthusiasm for research is a must ! |
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Student will be responsible for conducting novel research investigating the role of signaling pathways during the formation of embryonic organs. Numerous techniques will be used in order to examine this component of molecular development (organogenesis) using an amphibian model system. Participation in a research team.
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| molecular biology |
| developmental biology |
| embryology |
| cell signaling |
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